Microbiota, Immune Subversion, and Chronic Inflammation
نویسندگان
چکیده
منابع مشابه
Microbiota, Immune Subversion, and Chronic Inflammation
Several host-adapted pathogens and commensals have evolved mechanisms to evade the host innate immune system inducing a state of low-grade inflammation. Epidemiological studies have also documented the association of a subset of these microorganisms with chronic inflammatory disorders. In this review, we summarize recent studies demonstrating the role of the microbiota in chronic inflammatory d...
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The human gastrointestinal tract is occupied by a complex and abundant microbial community reaching as high as 10 13 –10 14 microorganisms in the colon. This micro-biota participates in a symbiotic relationship with their eukaryotic host, and this partnership is viewed as essential for maintaining homeostasis. The microbiome contains a wealth of information, encompassing 150-fold as many genes ...
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Inflammation is a multifactorial phenotype that in chronic kidney disease is associated with adverse patient outcomes. Recently, alterations in gut microbiota composition and intestinal barrier have been associated with inflammation and oxidative stress in CKD patients. Vanholder and Glorieux recently critically reviewed [Clin Kidney J (2015) 8 (2): 168-179] the current understanding of the rol...
متن کاملGut Microbiota and Inflammation
Systemic and local inflammation in relation to the resident microbiota of the human gastro-intestinal (GI) tract and administration of probiotics are the main themes of the present review. The dominating taxa of the human GI tract and their potential for aggravating or suppressing inflammation are described. The review focuses on human trials with probiotics and does not include in vitro studie...
متن کاملMicrobial subversion of the immune response.
A microbe becomes a pathogen by evading—to a greater or lesser extent—the immune defenses of its host. The mechanisms that have evolved for so doing are legion in number and striking in their diversity and ingenuity. They involve mechanisms to evade recognition by—and mechanisms to subvert the effector mechanisms of—both the innate and the adaptive immune response (see Table 1). All classes of ...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2017
ISSN: 1664-3224
DOI: 10.3389/fimmu.2017.00255